Human microbial ecology and stress

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Ескіз

Дата

2018

ORCID

DOI

Науковий ступінь

Рівень дисертації

Шифр та назва спеціальності

Рада захисту

Установа захисту

Науковий керівник

Члени комітету

Видавець

Анотація

Physical and psychological stress affects not only the immune system, but also hormonal and digestive homeostasis. Immune and neuroendocrine systems provide integrated responses to environmental signals, and the relationship between stress and immune function in many contexts, including a proliferative response to mitogens and cellular activity, has been demonstrated. Stress can lead to an imbalance between pro-and anti-inflammatory cytokines or uncontrolled production of cytokines. Dysregulation of congenital and adaptive intestinal immune responses directed against bacterial flora, including the destruction of oral tolerance to environmental antigens and commensals, are involved in several pathogenetic mechanisms. The integrity of intestinal microbiota can be influenced by some external factors, including the use of antibiotics, radiation, changes in the GIT, changes in the diet, psychological and physical stress. Psychological stress can directly affect the composition of the microflora, in particular with a noticeable decrease in lactic acid bacteria. GIT changes caused by stress factors make the conditions of the intestinal medium less favorable for survival, adhesion and replication of lactic acid bacteria.

Опис

Ключові слова

human microbial ecology, stress, мікробна екологія людини, стрес, кафедра біотехнології і мікробіології, микробная экология человека, стресс

Бібліографічний опис

Starovoitova, S. Human microbial ecology and stress / S. Starovoitova // Actual environmental problems. Proceedings of the VIII International Scientific Conference of young scientists, graduates, master and PhD students November 22–23, 2018. - Minsk, Republic of Belarus, 2018. – P. 81–82.