A possible general mechanism of the signal transfer on the α/β-interferons expression. 1. The local cell membrane deformation as the first induction stage

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dc.contributor.authorKarpov, Alexander
dc.date.accessioned2013-05-28T13:17:35Z
dc.date.available2013-05-28T13:17:35Z
dc.date.issued1998
dc.description.abstractA hypothetic mechanism of the external effect of viruses, synthetic polyaniones, double-stranded RNAs, and synthetic double-stranded polyribonucleotides upon a cell is explained. This effect is known to be followed by the α/β-interferons induction. Double-stranded RNAs and polynucleotides inducing such process are thought to change their conformation in an outer ionic perimembrane layer of cells and to induce the specific local deformation of cell membranes giving a signal for the α/β-interferons induction. In the case of viruses such a membrane deformation appears on the stage of virus penetration into the cell. The α/β-interferons inducers of intercalating nature are proposed to cause the interferonogenesis in vivo forming complexes with exogenic RNA molecules and stabilizing their double-stranded sites with a partial complementarity.uk_UK
dc.identifier.citationKarpov, O. A possible general mechanism of the signal transfer on the α/β-interferons expression. 1. The local cell membrane deformation as the first induction stage / O. Karpov // Біополімери і клітина. – 1998. – Т.14, №6. – С. 561-566.uk_UK
dc.identifier.urihttps://dspace.nuft.edu.ua/handle/123456789/8003
dc.language.isootheruk_UK
dc.subjectінтерферонuk_UK
dc.subjectіндукторuk_UK
dc.subjectвіруси поліаніониuk_UK
dc.subjectдволанцюгова РНКuk_UK
dc.subjectінтеркаляториuk_UK
dc.subjectinterferonuk_UK
dc.subjectinduceruk_UK
dc.subjectviruses polyanionsuk_UK
dc.subjectdouble-stranded RNAuk_UK
dc.subjectintercalatorsuk_UK
dc.subjectкафедра біотехнології і мікробіології
dc.titleA possible general mechanism of the signal transfer on the α/β-interferons expression. 1. The local cell membrane deformation as the first induction stageuk_UK
dc.typeArticleuk_UK

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