Regulation of Acetate Metabolism in a Strain of Acinetobacter sp. Growing on Ethanol

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dc.contributor.authorPirog, Tatianaen_EN
dc.contributor.authorKuzminska, Yu.en_EN
dc.date.accessioned2012-04-02T10:19:36Z
dc.date.available2012-04-02T10:19:36Z
dc.date.issued2003
dc.description.abstractEthanol metabolism in Acinetobacter sp. is shown to be limited by the rate of acetate assimilation,a reaction catalyzed by acetyl-CoA synthetase (EC 6.2.1.1). Effects of ions (sodium, potassium, and magnesium), by-products of ethanol and acetaldehyde oxidation (NADH and NADPH), and pantothenic acid on this enzyme are studied (sodium, NADH, and NADPH inhibit acetyl-CoA synthetase; pantothenic acid, potassium, and magnesium act as enzyme activators). Conditions of culturing were developed under which ethanol, acetaldehyde, and acetate in Acinetobacter cells were oxidized at the same rates, producing a threefold increase in the activity of acetyl-CoA synthetase in the cell-free extract. The results of studies of acetyl-CoA synthetase regulation in a mutant strain of Acinetobacter sp., which is incapable of forming exopolysaccharides, provide a basis for refining the technology of ethapolan production involving the use of C2 substrates.uk_UK
dc.identifier.citationPirog, T. Regulation of Acetate Metabolism in a Strain of Acinetobacter sp. Growing on Ethanol / T. Pirog, Yu. Kuzminska // Applied Biochemistry and Microbiology. - 2003. - Vol. 39, No. 2. - P. 158-165.
dc.identifier.urihttps://dspace.nuft.edu.ua/handle/123456789/667
dc.language.isoen_USuk_UK
dc.subjectethanol metabolismuk_UK
dc.subjectметаболизм этанолаuk_UK
dc.subjectacetyl-CoA synthetase
dc.subjectregulation
dc.subjectexopolysaccharides synthesis
dc.subjectацетил-КоА-синтетаза
dc.subjectрегуляция
dc.subjectсинтез экзополисахаридов
dc.subjectметаболізм етанолу
dc.subjectацетил-КоА-синтетаза
dc.subjectрегуляція
dc.subjectсинтез екзополісахаридів
dc.subjectкафедра біотехнології і мікробіології
dc.titleRegulation of Acetate Metabolism in a Strain of Acinetobacter sp. Growing on Ethanoluk_UK
dc.typeArticleuk_UK

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