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Документ Synthesis of novel pyrazole based aurones(2022) Myshko, Andrii; Mrug, Galyna; Kondratyuk, Kostyantyn; Demydchuk, Bohdan; Bondarenko, Svetlana; Frasinyuk, MihayloAs we found, simplest pyrazole based aurone analogs could be obtained by Claisen-Shmidt condensation of hydroxylated or alkoxylated benzofuran-3(2H)-ones and 3(5)-pyrazolecarboxaldehyde or 4-pyrazolecarboxaldehyde under action of KOH in EtOH. For the synthesis of hydroxypyrazole based aurone analogs we choose condensation of masked enaminones as synthetic equivalent of 3-hydroxy-4-formylpyrazoles/4-formylpyrazolin-3-ones. Target aurones were obtained by refluxing of benzofuranones with masked aldehydes in acetic acid