Перегляд за Автор "Shkotova, Lyudmila"

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Bacteriocins Lactobacillus – an alternative to antimicrobial drugs
(2021) Voloshina, Iryna; Soloshenko, Kateryna; Krasinko, Victoria; Lych (Tkachenko), Inna; Shkotova, Lyudmila
The review presents the characteristics of bacteria of the Lactobacillus family and their ability to synthesize various bacteriocins. The classification of lactobacilli bacteriocins is given, which includes three classes: class I – lantibiotics (peptides with a molecular weight of less than 5 kDa, which containing lanthionine), class II – unmodified bacteriocins, also called non-lantibiotics (heat-resistant peptides, which do not contain lanthionine and have a molecular weight of less 10 kDa) and class III – a poorly studied group of thermolabile proteins with a molecular weight of more than 30 kDa. Lactobacilli are shown to synthesize a wide spectrum of bacteriocins, which demonstrate a variety of actions and are able to inhibit the growth of numerous species of opportunistic gram-positive microflora. The article also provides the examples of lactobacilli bacteriocins isolated from food products (fermented meat, fish, kombucha, goat milk, koumiss, etc.) and various human biotopes (microbiota of breast milk, intestinal tract, and vaginal secretions). Additionally, the review shows the prospects of wide application of bacteriocins synthesized by lactobacilli in the food and pharmaceutical industries.
Polyfunctional properties of goat colostrum proteins and their use
(2020) Soloshenko, Kateryna; Lych (Tkachenko), Inna; Voloshina, Iryna; Shkotova, Lyudmila
The review presents the composition of goat colostrum, antimicrobial, immunomodulatory and antioxidant properties of biologically active proteins of goat colostrum, as well as the prospects of their use in medicine. Due to the presence of a complex of biologically active proteins such as lactoferrin, lysozyme, lactoperoxidase, immunoglobulins, etc., goat colostrum increases the body’s resistance to infectious diseases, strengthens the immune system, has an antioxidant effect and antibacterial activity against a wide range of microorganisms, thereby preventing or delaying chronic diseases associated with the oxidative stress. Additionally, goat colostrum bioactive proteins show antitumor activity, antiatherogenic properties, the ability to lower the blood pressure and efficiency in the treatment of rheumatoid arthritis.
Practical use of goat milk and colostrum
(2021) Voloshina, Iryna; Soloshenko, Kateryna; Lych (Tkachenko), Inna; Shkotova, Lyudmila
This review presents the protein and amino acid composition of both goat colostrums and milk and describes the properties of goat colostrums and milk components. In addition, the prospects of use of goat milk and colostrum in the food and cosmetics industry and the feasibility of use of goat milk for baby feeding are shown. Functional foods produced from goat milk have antioxidant, anti-inflammatory, cardioprotective, antihypertensive and antiatherogenic activities in the human body. Goat milk cosmetics are very useful for maintaining a healthy skin and are effective in treatment of various skin diseases. Infant formula based on goat milk provides comfortable digestion for babies and are better at absorbing proteins, fats and other nutrients than infant formula based on cow’s milk.