Antiviral activity of 1,2,4-triazole derivatives (microreview)

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dc.contributor.authorSimurova, Natalia
dc.contributor.authorMayboroda, Elena
dc.date.accessioned2022-02-23T19:01:08Z
dc.date.available2022-02-23T19:01:08Z
dc.date.issued2021
dc.description.abstractToday, 1,2,4-triazole derivatives are the preferred structural moieties in the development of new drugs with a wide range of pharmacological activity, as evidenced by several reviews.This is due to the fact that the triazole ring can be considered a bioisostere of an amide, ester, or carboxyl groups. Relatively low toxicity, good pharmacokinetic and pharmacodynamic properties of triazole, its resistance to metabolic degradation are another advantages. In recent years, against the background of the emergence of new viral infections and the lack of effective chemotherapeutic agents for their treatment, the number of studies on the antiviral properties of 1,2,4-triazole derivatives has significantly increased. In the presented review, we focused on current publications devoted to the study of the antiviral properties of compounds containing the 1,2,4-triazole ring. Isosteric analogs of known drugs, as well as new molecules, are considered.uk_UA
dc.identifier.citationSimurova, N. Antiviral activity of 1,2,4-triazole derivatives (microreview) / N. Simurova, O. Mayboroda // Chemistry of Heterocyclic Compounds – 2021. – Vol. 57, Issue 4. – P. 420–422.uk_UA
dc.identifier.urihttps://dspace.nuft.edu.ua/handle/123456789/37147
dc.language.isoenuk_UA
dc.subjectтриазолuk_UA
dc.subjectвірусні інфекціїuk_UA
dc.subjectпротивірусні засобиuk_UA
dc.subjecttriazoleuk_UA
dc.subjectviral infectionsuk_UA
dc.subjectantiviral drugsuk_UA
dc.subjectкафедра харчової хіміїuk_UA
dc.titleAntiviral activity of 1,2,4-triazole derivatives (microreview)uk_UA
dc.typeArticleuk_UA

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