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Постійне посилання на розділhttps://dspace.nuft.edu.ua/handle/123456789/7372

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Synthesis of formononetin analogs
(2003) Bondarenko, Svetlana; Frasinyuk, Mihaylo; Khilya, Volodimir
Derivatives of the natural isoflavone formononetin were synthesized. Acylation and alkylation of the phenolic hydroxyls and the chromone ring were investigated.
Synthesis of 3',4'-dimethoxyisoflavone derivatives
(2003) Bondarenko, Svetlana; Frasinyuk, Mihaylo; Khilya, Volodimir
2-(Un)substituted-3',4'-dimethoxy-7-hydroxyisoflavones were synthesized. Their derivatives substituted at the phenolic hydroxyl were prepared by alkylation and acylation. Aminomethyl derivatives were also prepared.
Synthesis of pseudobaptigenin analogs
(2003) Bondarenko, Svetlana; Frasinyuk, Mihaylo; Khilya, Volodimir
Homologs of the natural isoflavonoid pseudobaptigenin containing benzodioxane and benzodioxepane fragments were synthesized. Methanesulfonyl, carbamoyl, aminomethyl, and coumarin-containing isoflavone derivatives were prepared.
Features of the aminomethylation of 7-hydroxy-4'-fluoroisoflavones with primary amines
(2010) Bondarenko, Svetlana; Frasinyuk, Mihaylo; Khilya, Volodimir
The behavior of 7-hydroxy-4'-fluoroisoflavones under the conditions of the Mannich reaction with primary amines was studied. New 9-alkyl-substituted 3-(4-fluorophenyl)-9,10-dihydro-4H,8H-chromeno-[8,7-e][1,3]oxazin-4-ones were synthesized. A method was developed for the synthesis of 8-amino- methyl derivatives of isoflavones.