A possible general mechanism of the signal transfer switching on the α/β-interferons expression. 2. The role of the cAMP in the process of the interferon induction
Дата
1999
Автори
ORCID
DOI
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Видавець
Анотація
The author carries out an analysis of available data concerning the participation of cyclic adenosine-3’,5’-monophosphate (cAMP) in the signal transduction pathway on the α/β-interferons (IFN) expression during the induction process/ The cAMP is known to participate in the activation of protein kinases during the interferon induction as well as of nuclear factors activating specifically the regulating domains of IFN genes. The cAMP is thought to be a secondary key messenger mediating the signal for α/β-IFN induction, the first stage of this induction being the local cell membrane deformation caused by different inducers.
Опис
Ключові слова
інтерферон, індукція, циклічний аденозин-3’,5’-монофосфат, протеїнкінази, ядерні фактори, interferon, induction, cyclic adenosine-3’,5’-monophosphate, proteinkinases, nuclear factors, кафедра біотехнології і мікробіології
Бібліографічний опис
Karpov, O. A possible general mechanism of the signal transfer switching on the α/β-interferons expression. 2. The role of the cAMP in the process of the interferon induction / Karpov, O. // Биополимеры и клетка. – 1999. – Т. 15, №1. – С. 83-86.