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Документ Selection of fermenter with optimal characteristics for batch process of microbial synthesis(2013) Karlash, Yuri; Gerasimenko, VsevolodThe global technical-economic criteria of optimization can be used for the selection of the most effective fermenter for bath process of microbial synthesis. The algorithm for this criteria calculation was developed using software MathCAD. This calculated optimization criteria considers the physiological properties of cultivated microorganism, composition of nutrient medium and the cost of each component, energy consumption for mixing and aeration, capital costs for purchase and installation of fermenter, as well as for its amortization. Comparative studies of different types of fermenters from created database allow to choose the most effective fermenter with the optimal characteristics and to minimize expenses for realization of fermentation process.Документ Micro- and macro-mixing effect in case of intensification and scaling-up of transfer processes in bioreactors(1992) Loboda, Pavel; Karlash, YuriOffered are the combined analytical dependences linking parameters of biosynthesis with characteristics of micro- and macro-mixing level in the case of intensification and scaling-up of biosynthesis processes.Carried out was an experimental check of the suggected analytical dependences in the case of scaling-up of bioreactors with vibro-mixing (after the autors' design) and routine stirred bioreactors.Документ Biotechnology of the suspension cultivation of cells sensitive to mechanical effects(1992) Karlash, Yuri; Povodzinsky, Vadim; Dumanskiy, ValentinInvestigated and introduced into industry is the technology of getting interferons in fermemers provided with vibration and pulsation mixing (after the autors' desing).The results obtained testify to the effectiveness of use of the vibration and pulsation mixing for biotechnology of the suspension cultivation of tissue and filamentuos cultures.