Тези доповідей

Постійне посилання колекціїhttps://dspace.nuft.edu.ua/handle/123456789/7497

Переглянути

Фільтри

20242

Налаштування

Ключове слово: search.filters.subject.food supplement

Результати пошуку

Зараз показуємо 1 - 2 з 2
  • Ескіз
    Документ
    Potential of probiotic strains as basis of food supplement for managing cardiovascular health: a focus on hypocholesterolemic activity and prevention of high cholesterol-related conditions
    (2024) Starovoitova, Svitlana; Demchenko, Olga; Kishko, Karina; Spivak, Mykola
    The obtained results allow us to assert that it is necessary to develop a line of food supplements and probiotics, based on the studied strains and their compositions in encapsulated form (which will increase the survival of probiotic microorganisms when passing through the upper gastrointestinal tract, which will indirectly increase the therapeutic effect of such drugs and products) , for prevention and treatment of diseases associated with the negative manifestations of high cholesterol levels. Probiotics that contain cholesterol-assimilating strains can efficiently complete the complex therapy of CVD, cancer etc
  • Ескіз
    Документ
    Probiotic strains with hypocholesterolemic activity as potential basis of food supplement for prevention and concomitant treatment of cardiovascular diseases associated with high cholesterol level
    (2024) Starovoitova, Svitlana; Spivak, Mykola
    Globally, about 17 million people die from cardiovascular disease (CVD) every year, accounting for 31% of all deaths worldwide. High serum cholesterol is regarded by many as the main cause of coronary atherosclerosis, and it has been well established that elevated cholesterol is associated with an increased risk of CVD. Apart from modulating the gut functionality, probiotics have also been associated with various other health benefits such as brain functioning, boosting immunity, reducing cholesterol, and promoting metabolic homeostasis through their biological mechanisms in the body. Several mechanisms of involvement of the microbiome in maintaining lipid metabolism at a physiological level and preventing the development of hypercholesterolemia are assumed: deconjugation of bile acids and reduction of their resorption due to the synthesis of specialized hydrolases; incorporation of cholesterol into the lipid layer of the cell membrane; transformation of cholesterol into coprostanol and its removal from the body together with feces; inhibition of cholesterol synthesis in the liver.